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Hamilton Thorne Biosciences, Inc.
Hamilton Thorne Biosciences, Inc., is a private
DNA technology company with a focus on developing products that can
fundamentally improve drug discovery and the practice of medicine. We are
developing a portfolio of technologies for the detection and quantification of
proteins and nucleic acids, with companion electronic automation for the
location, detection and analysis of rare cells in clinical samples (rare
events).
Our single-temperature (isothermal) detection
platform, RAM (Ramification Amplification Method), can increase discrimination
power up to 1000 fold above current methods. RAM and its companion technology,
HSAM (Hybridization Signal Amplification Method), represent the next generation
of technology after PCR (polymerase chain reaction). RAM/HSAM have significant
advantages in sensitivity, multiplexing, quantification, and dynamic range over
older amplification methods and offer real-time, super-exponential
amplification.
In the clinic of the future, where "labs on a
chip," microarrays and microfluidics can require small sample size, our
technology will offer critical advantages. Our proprietary techniques provide
reliable and repeatable DNA analysis, whether the sample holds one cell or
thousands. Earliest detection of cancer recurrence, monitoring response to
therapy for immunocompromised patients and prenatal testing of fetal cells from
maternal peripheral blood are all applications where rare event analysis offers
a medical breakthrough.
The ease of use, low cost and accuracy of our
products gives us a signal opportunity to forge a leadership position in
clinical research, drug development, earliest disease diagnosis and thus
effective patient treatment. With the opportunity for HT's complete automation
and single step processing, DNA analysis can become a practical reality in a
broad range of applications, including proteomics, genomics, and diagnostics.
Careers at
Hamilton Thorne Biosciences, Inc.
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If there are no current openings in your area of
interest, we will gladly accept resumes for future opportunities. Those with
backgrounds in molecular biology are especially encouraged.
Please send resume and letter of interest by
e-mail, fax or post to:
Richard
Williamson, Operations Manager
Hamilton Thorne Biosciences, Inc.
100 Cummings Center, Suite 102C
Beverly, MA 01915
Fax: (978) 921-2050
rfw@hamiltonthorne.com |